Pasireotide

REQUEST QUOTATION

CAS number:
396091-73-9

Sequence
Cyclo(Phg-D-Trp-Lys-Tyr(Bzl)-Phe-Hyp(2-aminoethyl-carbamoyl))

Molecular formula: C58H66N10O9

Molecular weight: 1047.2 a.m.u.

Fields of Application
Acromegaly
Cushing’s disease

Description
Pasireotide is a synthetic peptide analogue of somatostatin that resembles the native hormone in its ability to suppress levels and activity of growth hormone, insulin, glucagon and many other gastrointestinal peptides. Because its half-life is longer than somatostatin, pasireotide can be used clinically to treat neuroendocrine pituitary tumors that secrete excessive amounts of growth hormone causing acromegaly, or adrenocorticotropic hormone (ACTH) causing Cushing disease.

Administration:
Regular injectable form.