Thymosin A1

REQUEST QUOTATION

CAS number: 
62304-98-7

Sequence
As-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH

Molecular formula: C129H215N33O55

Molecular weight: 3108.3 a.m.u.

Fields of Application
Hepatitis B and C

Description
The thymus gland controls the development of T-lymphocytes and thereby plays a central role in cell-mediated immunity and in the regulation of immune responses. Several polypeptides characterised in the thymus or serum are able to induce lymphocyte differentiation in vitro and in vivo.

Thymosin A1, also known as Thymalfasin is used alone or in combination with interferon as an immunomodulator for the treatment of chronic hepatitis B and C. It is also used to enhance the effectiveness of influenza vaccines in immunocompromised or elderly patients and of influenza and hepatitis B vaccines in chronic haemodialysis patients.

Thymosin A1 is under investigation for a number of other diseases, including hepatitis D, hepatocellular carcinoma, non-small cell lung cancer, melanoma, and HIV infection and AIDS.

Administration:
Regular injectable form.

Thimosin a1