Lanreotide

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CAS number:
108736-35-2

Sequence
cyclo(Cys(2)-Cys(7)) H-D-2-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2

Molecular formula: C54H69N11O10S2

Molecular weight: 1096.3 a.m.u.

Fields of Application
Acromegaly
Neuroendocrine tumors (carcinoid syndrome and VIPomas)
Polycystic liver disease

Description
Lanreotide is a synthetic analogue of somatostatin, a naturally occurring inhibitory hormone which blocks the release of several other hormones, including growth hormone, thyroid-stimulating hormone (TSH), insulin and glucagon. Lanreotide binds to the same receptors as somatostatin, although with higher affinity to peripheral receptors, and has similar activity. However, while somatostatin is quickly broken down in the body, lanreotide has a much longer half-life, and produces far more prolonged effects.

Administration:
Regular injectable form.