Molecular formula: C45H69N11O12S
Molecular weight: 988.2 a.m.u.
Fields of Application
Prevention of bleeding after caesarean
Induction of milk production
Veterinary: Induction of milk production
Carbetocin is an oxytocin analogue with modifications in the terminal Cysteine residue and in the disulphur bridge betwen Cys1 and Cys6. Carbetocin lacks cysteine residue in position 1, the disulphur has been substituted by a thioether linkage and the phenolic alcohol is blocked by a methyl ether.
It is reported that Carbetocin has a longer duration of action than Oxytocin. It is used for the prevention of uterine atony and excessive bleeding following caesarean.
It is also sometimes used to help milk secretion in breast-feeding.
Carbetocin is also used in veterinary medicine.
Regular injectable form.