Molecular formula: C60H86N16O13
Molecular weight: 1239.5 a.m.u.
Fields of Application
Prostate Cancer and Endometriosis
Precocious central puberty
Veterinary: Induction of ovulation (cows, mares and rabbits)
Treatment of ovarian disorders
Buserelin is a synthetic nonapeptide analogue of human Gonatropin-releasing hormone (LH-RH) with agonistic activity to gonadorelin.
It is used to treat cancer of the prostate gland. Intranasal and subcutaneous buserelin have demonstrated efficacy in a variety of conditions, including endometriosis, uterine leiomyoma, advanced prostate cancer, polycystic ovary syndrome, central precocious puberty. It has also enhanced success rates of in-vitro fertilization programs. However, comparative trials with other LH-RH analogs (e.g. leuprolide, goserelin) are necessary to establish the place in therapy of buserelin.
Regular injectable form and Nasal spray.